Phenylpropanoids and polyketides
Medchemexpress LLC Myricetin | 529-44-2 | C15H10O8 | 25 MG
Myricetin is a plant-derived flavonoid with strong antioxidant, anticancer, antidiabetic, and anti-inflammatory properties. It exhibits scavenging activity against radicals and ions, prevents cancer cell death via apoptosis through PI3K/Akt and MAPK signaling, and shows antiphotoaging effects by quenching free radicals in the skin. It also inhibits ovarian cancer cell viability and human Hsp70.
- Strong antioxidant, anticancer, antidiabetic, and anti-inflammatory activities
- Scavenges various radicals and ions
- Prevents cancer cell death via apoptosis
- Exhibits antiphotoaging effects in skin
- Suppresses UVB-induced COX-2 expression
- Inhibits UVB-induced initiation of activator protein-1 and NF-κβ
- Inhibits Fyn kinase activity
- Inhibits viability of SKOV3 ovarian cancer cells
- Induces DNA DSBs and ER stress leading to apoptosis
- Inhibits human Hsp70
Apexbio Technology LLC BIIE 0246 246146-55-4 10mg
BIIE 0246 (CAS 246146-55-4) is a potent and selective antagonist of the neuropeptide Y Y2 receptor (Y2R) a G protein-coupled receptor involved in presynaptic inhibition within the central and peripheral nervous systems BIIE 0246 exhibits high affinity for Y2R with an IC50 of 3 3 nM in radioligand binding assays and Ki values between 8 15 nM in HEK293 cells expressing rat Y2 receptors In hippocampal slices BIIE 0246 (100 nM) reverses NPY-induced inhibition of excitatory postsynaptic potentials In vivo administration in rats attenuates PYY(3-36)-mediated suppression of food intake and increases feeding in satiated animals supporting its use in research on appetite regulation and anxiety-related behavior
Medchemexpress LLC Seratrodast | 112665-43-7 | 99.6% | 25 MG
Seratrodast (AA 2414) is an orally active antiasthmatic agent, a thromboxane A2 receptor (TP) antagonist, and a ferroptosis inhibitor. It reduces lipid ROS production, modulates the systemic xc-/GSH/GPX4 axis, and inhibits JNK phosphorylation and p53 expression. This compound exhibits anti-asthmatic and anti-epileptic activity.
- Thromboxane A2 receptor (TP) antagonist
- Ferroptosis inhibitor
- Reduces lipid ROS production
- Modulates the systemic xc-/GSH/GPX4 axis
- Inhibits JNK phosphorylation and p53 expression
- Exhibits anti-asthmatic activity
- Exhibits anti-epileptic activity
- For research use only
eMolecules AstaTech / 11-DIPHENYLACETONE / 1g / 718063641 / D89851 / 95.000 / 781-35-1 / MFCD00008759 / 210.276 / C15H14O
AstaTech / 11-DIPHENYLACETONE / 1g / 718063641 / D89851 / 95.000 / 781-35-1 / MFCD00008759 / 210.276 / C15H14O
Medchemexpress LLC Ferulic acid methyl ester | 2309-07-1 | 99.9% | 208.21 g/mol | C11H12O4 | 1 G
Ferulic acid methyl ester (methyl ferulate) is the methyl ester derivative of ferulic acid used as a research reagent. It is reported as a p38 MAPK inhibitor with anti-inflammatory and antioxidant properties and is applied in studies of autophagy and neurological disease. The compound is cell membrane and brain permeable and modulates COX-2, p-p38, and p-JNK signaling.
- CAS number 2309-07-1
- Chemical formula C11H12O4
- Molecular weight 208.21 g/mol
- Typical purity ~99.9% (rounded)
- Available as solid and 10 mM solution in DMSO
- Reported p38 MAPK inhibitor with anti-inflammatory activity
- Useful for autophagy and neurological disease research
Medchemexpress LLC 3-aminochromen-2-one | 1635-31-0 | MFCD00016965 | 99.2% | 161.16 | C9H7NO2 | 500 MG
3-aminochromen-2-one is a coumarin-derived organic compound used primarily as a synthetic intermediate in coordination chemistry and organic synthesis. It is employed as a building block for the preparation of metal complexes and functionalized coumarin derivatives for research use. Chemical formula C9H7NO2; molecular weight 161.16.
- Used as an intermediate for synthesis of metal complexes.
- Can act as a ligand in coordination chemistry.
- Serves as a building block for fluorescent coumarin derivatives.
- Suitable for research-scale synthetic applications.
- Characterized by known molecular formula and molecular weight.
Medchemexpress LLC (-)-Epigallocatechin | 970-74-1 | 306.27 | 5 MG
(-)-Epigallocatechin (Epigallocatechin) is the most abundant flavonoid in green tea. It can bind to unfolded native polypeptides and prevent their conversion to amyloid fibrils. This compound has been researched for its biological activity in various applications.
- Targets MMP and autophagy
- Classified as a flavonoid, flavanol, phenol, and polyphenol
- Derived from Camellia sinensis (L.) O. Ktze.
- Potent inhibitor of amyloidogenic cystatin I66Q amyloid fibril formation in vitro
- Prevents amyloidogenic cystatin fibril formation by stabilizing the molecule
- Inhibits STAT3 phosphorylation and STAT3-NFkB interaction
- Effectively eradicates E. faecalis biofilms
- Induces hydroxyl radicals in E. faecalis
- Induces significant down-regulation of E. faecalis virulence genes
Cell Signaling Technology Phospho-Akt (Thr308) (C31E5E) Rabbit mAb 20 ul
Phospho-Akt (Thr308) (C31E5E) Rabbit mAb 20 ul
Medchemexpress LLC Ethyl benzoate | 93-89-0 | MFCD00009109 | 99.9% | 150.17 g/mol | C9H10O2 | 1 ML
Ethyl benzoate is an organic ester (C9H10O2) provided as a ready-to-use 10 mM solution in DMSO for research and analytical applications. It is used as a reference standard and reagent for analytical method development, chromatography, and biochemical assays that require a defined concentration and high purity (CAS 93-89-0).
- Ready-to-use 10 mM solution in DMSO.
- High purity suitable for analytical use.
- Convenient 1 mL volume for small-scale assays.
- Accompanied by safety data and certificate of analysis.
- Suitable for chromatography and method development as a reference standard.
FUJIFILM BIOSCIENCES INC 4 4 -BIS(2-SULFOSTYRYL)BIPHENY
*Orders for this supplier are non-cancellable/non-returnable once they are processed.* 4,4'-Bis(2-sulfostyryl)biphenyl Disodium Salt 5GR
eMolecules ChemScene / 44-Methylenebis(NN-diethylaniline) / 1g / 591908855 / CS-0152033 / 0.000 / 135-91-1 / MFCD00071778 / 310.485 / C21H30N2
ChemScene / 44-Methylenebis(NN-diethylaniline) / 1g / 591908855 / CS-0152033 / 0.000 / 135-91-1 / MFCD00071778 / 310.485 / C21H30N2
Medchemexpress LLC Oxytetracycline (hydrochloride) | 2058-46-0 | 98.9% | 25 MG
Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class, known for its potent inhibition of Gram-negative and Gram-positive bacteria. This compound acts as a protein synthesis inhibitor, preventing the binding of aminoacyl-tRNA to the m-ribosomal RNA complex. It also exhibits anti-HSV-1 activity and is synthesized by a type II polyketide synthase. This product is for research use only.
- Potently inhibits Gram-negative bacteria
- Potently inhibits Gram-positive bacteria
- Functions as a protein synthesis inhibitor
- Prevents aminoacyl-tRNA binding to m-ribosomal RNA complex
- Exhibits anti-HSV-1 activity
- Stable under recommended storage conditions
- Appears as a light yellow to yellow solid